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Introducing CurveX™: A New Frontier in Peyronie’s Disease Treatment

A New Frontier in Peyronie’s Disease Treatment

At Menspro Health™, we’re excited to launch CurveX™—a cutting-edge, non-surgical treatment protocol for Peyronie’s Disease (PD). With an estimated 9% of men affected by this condition, the need for effective treatments is clear. We’re proud to offer one of the most comprehensive approaches in the U.S., combining CurveX™ with proven options like Xiaflex®, Acoustic Wave Therapy with Platelet-Rich Plasma (PRP), Vacuum Erection Devices (VEDs), and Verapamil injections for acute cases.

What Is Peyronie’s Disease?

Peyronie’s Disease occurs when fibrous scar tissue, or plaque, forms inside the penis—often due to injury or trauma—causing curved, sometimes painful erections. This can affect both function and confidence, with severity ranging from mild to significant curvature, and in some cases, indentations or “hourglass” deformities from scar contraction. For men with mild to moderate PD and intact erectile function, conservative options like Xiaflex can help, but effectiveness tends to decrease as curvature worsens. For severe cases, surgery remains the most reliable approach.

What Makes CurveX™ Different?

CurveX™ is a minimally invasive, injection-based protocol developed by our expert team, led by Dr. Hugh Smith of Menspro Health™ and Deborah Parker of Belcourt Aesthetics. It uses Hyaluronic Acid (HA)—a naturally occurring substance widely used in regenerative medicine—administered off-label to target penile plaque and correct aesthetic defects. When precisely injected into the plaque, HA may soften scar tissue and support tissue remodeling to reduce curvature. Additionally, HA can be used to fill in divots, indentations, or “hourglass” deformities caused by scar contraction, enhancing penile appearance and stabilizing erections. Unlike Xiaflex, which carries a small (0.5-0.7%) risk of penile fracture, HA has not been shown to increase this risk, offering a versatile and safer option for conservative treatment.

No other clinic in the country combines this array of PD treatments, making Menspro Health™ a leader in non-surgical urological care.

A Full Spectrum of Options

At Menspro Health™, we personalize your care with a range of advanced treatments:

  • Xiaflex®: The only FDA-approved injectable for PD, suitable for mild to moderate cases with intact erectile function.
  • CurveX™: Our pioneering HA-based option, designed as an alternative for similar cases, with no known fracture risk and added aesthetic benefits.
  • Acoustic Wave Therapy with PRP: A non-invasive therapy combining low-intensity shockwaves and platelet-rich plasma to promote tissue health, reduce pain, and support penile rehabilitation. In our clinics, we’ve seen encouraging results with this approach, particularly for pain relief and modest curvature improvement in early PD cases.
  • Vacuum Erection Devices (VEDs): A complementary tool that uses suction to improve blood flow, often paired with acoustic wave therapy and PRP for enhanced outcomes.
  • Verapamil Injections: An option for very acute PD cases, delivering a calcium channel blocker to potentially reduce plaque formation and inflammation early on.

No other clinic in the country combines this array of PD treatments, making Menspro Health™ a leader in non-surgical urological care.

Potential Benefits of CurveX™

  • Targets plaque with precision intralesional injections
  • May reduce curvature and improve function
  • Fills in defects like divots or “hourglass” shapes for better aesthetics
  • May stabilize erections by addressing scar-related deformities
  • Minimally invasive with little to no downtime
  • An option for men seeking conservative treatment in acute or chronic PD phases
  • No associated penile fracture risk (unlike Xiaflex)

Additional Note: Acoustic Wave Therapy and/or PRP may help reduce pain and improve curvature, especially in early PD, based on clinical studies and our own experience, though results vary. All treatments require a consultation to assess suitability, as outcomes depend on individual factors and further research is ongoing.

Articles & Independent Studies:

Intraplaque injections of hyaluronic acid for the treatment of stable-phase Peyronie’s disease: a retrospective single-center experience

Cilio S, Rocca R, Celentano G, Marino C, Creta M, Califano G, Manfredi C, Russo GI, Morgado A, Falcone M, Capece M; YAU Working Group Sexual and Reproductive Health. Intraplaque injections of hyaluronic acid for the treatment of stable-phase Peyronie’s disease: a retrospective single-center experience. Asian J Androl. 2024 May 1;26(3):268-271. doi: 10.4103/aja202371. Epub 2024 Feb 2. PMID: 38305689; PMCID: PMC11156460.
Current Evidence on the Use of Hyaluronic Acid as Nonsurgical Option for the Treatment of Peyronie’s Disease: A Contemporary Review

MDPI and ACS Style
Capece, M.; Celentano, G.; La Rocca, R. Current Evidence on the Use of Hyaluronic Acid as Nonsurgical Option for the Treatment of Peyronie’s Disease: A Contemporary Review. Uro 2023, 3, 160-167. https://doi.org/10.3390/uro3020017

AMA Style
Capece M, Celentano G, La Rocca R. Current Evidence on the Use of Hyaluronic Acid as Nonsurgical Option for the Treatment of Peyronie’s Disease: A Contemporary Review. Uro. 2023; 3(2):160-167. https://doi.org/10.3390/uro3020017

Chicago/Turabian Style
Capece, Marco, Giuseppe Celentano, and Roberto La Rocca. 2023. “Current Evidence on the Use of Hyaluronic Acid as Nonsurgical Option for the Treatment of Peyronie’s Disease: A Contemporary Review” Uro 3, no. 2: 160-167. https://doi.org/10.3390/uro3020017

APA Style
Capece, M., Celentano, G., & La Rocca, R. (2023). Current Evidence on the Use of Hyaluronic Acid as Nonsurgical Option for the Treatment of Peyronie’s Disease: A Contemporary Review. Uro, 3(2), 160-167. https://doi.org/10.3390/uro3020017

EFFICACY AND SAFETY OF INTRALESIONAL INJECTION OF HYALURONIC ACID (HA) FOR THE TREATMENT OF CHRONIC PHASE PEYRONIE’S DISEASE (PD): PRELIMINARY RESULTS FROM A PILOT STUDY
Marino Dr. Claudio, D’Alterio Dr. Carlo, Giordano Dr. Alessandro, di Giovanni Dr. Angelo, Verze Prof. Paolo, Cirigliano Dr. Lorenzo, Capece Prof. Marco, La Rocca Prof. Roberto, (206) EFFICACY AND SAFETY OF INTRALESIONAL INJECTION OF HYALURONIC ACID (HA) FOR THE TREATMENT OF CHRONIC PHASE PEYRONIE’S DISEASE (PD): PRELIMINARY RESULTS FROM A PILOT STUDY, The Journal of Sexual Medicine, Volume 20, Issue Supplement_4, July 2023, qdad062.127, https://doi.org/10.1093/jsxmed/qdad062.127
 

Be Among The First to Experience Menspro CurveX™

Why It Matters: Meeting an Unmet Need

For the 9% of men with PD, treatment options depend on severity. While surgery is the gold standard for severe curvature or significant erectile dysfunction, many prefer less invasive approaches for milder cases. CurveX™, alongside our expanded offerings, provides promising alternatives, with early experiences in our clinics showing encouragement. We’re dedicated to providing choices for men who want to explore conservative options first—as long as they understand surgery may ultimately be the most effective for severe PD.

Our Honest Answer: Your Path Forward

At Menspro Health™, we believe in straight talk and real results. When you come in, our expert medical team will evaluate your condition with care and give you an honest, no-nonsense answer about your best options—whether that’s CurveX™, Xiaflex, acoustic wave therapy with PRP, VEDs, verapamil, or surgery. Together, we’ll weigh the pros and cons, discuss the risks, benefits, and potential outcomes of all your options, and answer your questions to empower you to make an informed decision that’s right for you. No hype, just clarity—because your health deserves nothing less.

Do You Qualify for CurveX™ or Our Other Treatments?

The first step to finding the right treatment is understanding your condition. Book a medical consultation and exam with our specialists for just $99—and that $99 goes toward the cost of your treatment if you proceed. During your visit, we’ll:

  • Examine the penis to locate and assess plaque and any deformities
  • Determine if CurveX™, Xiaflex, acoustic wave therapy with PRP, VEDs, or verapamil is right for you—or if surgery is recommended
  • Discuss your symptoms, history, and goals

Not sure where to start? Take our quick online quiz to see if you might be a candidate: Click here to take the candidacy quiz (#). Then, schedule your $99 consultation to get personalized answers and take control of your health.

Take Control of Your Health Today

Don’t wait to explore your options. For just $99, you can get a full medical consultation and exam with our expert team—and that $99 will be credited toward any treatment you choose. With Menspro Health™, you’re not limited to one-size-fits-all approaches. Contact us now to book your appointment and learn how our unmatched range of effective treatments—including CurveX™—can help you regain confidence and comfort.

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